If you stay indoors, you don't have to worry about the weather.
Once you reach 500,000 ants you can fight and beat anything, including; the anteater, the exterminator, the police and the army. At this point it becomes very easy to reach 1000,000,000 ants (by switching between food gathering and nursing). Try and buy all the bonuses as quickly as possible, without wasting gems to buy food a or increase nest size. I finished my last game after 957 game days (about 4 hours).